Study Clears Tylenol for Pregnancy After Autism Claims

Pregnant women can breathe easier today. A comprehensive study published in The Lancet has found zero evidence linking paracetamol (known as Tylenol in the US) to autism in babies, putting to rest fears that spread after controversial public health warnings last year.

The systematic review analyzed 43 clinical studies from around the world. Researchers found no meaningful increase in autism spectrum disorder, ADHD, or intellectual disability among children whose mothers took paracetamol as directed during pregnancy.

The timing matters. In September 2025, President Trump advised pregnant women to avoid Tylenol, claiming it caused autism in infants. His statement sent waves of concern through expecting families and their doctors.

Lead researcher Francesco D'Antonio and his team wanted definitive answers. They examined every major study on the topic, including long-term research following children for more than five years. The conclusion remained the same: no connection exists between properly used paracetamol and developmental disorders.

Paracetamol is the most commonly used pain reliever during pregnancy worldwide. The World Health Organization lists it as an essential medicine because it treats fever and pain more safely than alternatives like opioids or anti-inflammatory drugs.

The Bright Side

This research does more than clear up confusion. It actually protects mothers and babies from real danger.

Untreated fever during pregnancy carries proven risks: miscarriage, birth defects, preterm birth, and developmental problems in children. Severe untreated pain poses similar threats. By confirming paracetamol's safety, doctors can continue treating these conditions without hesitation.

The findings support guidance from major medical organizations including the American College of Obstetricians and Gynecologists and the Royal College of Obstetricians and Gynaecologists. All continue recommending paracetamol as the first choice for pain and fever in pregnancy.

The researchers emphasized a crucial point: avoiding paracetamol based on unproven fears could cause greater harm than the medication itself. Pregnant women deserve access to safe, effective treatment when they need it.

For the millions of expectant mothers who take paracetamol each year, this peer-reviewed research offers something invaluable: peace of mind backed by solid science.